On Friday, Sept. 27 at 7:10 p.m. ET, the Cleveland Guardians (92-67) host the Houston Astros (86-73) at Progressive Field in the series opener. Joey Cantillo will get the nod for the Guardians, while Ronel Blanco will take the mound for the Astros.

The Guardians (-125), according to bookmakers, are moneyline favorites in this matchup versus the Astros (+105) This game’s over/under has been set at 8. You can get -105 odds on the over and -115 odds on the under.

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Astros vs. Guardians Game Info

• Date: Friday, September 27, 2024
• Time: 7:10 p.m. ET
• Location: Cleveland, Ohio
• Venue: Progressive Field
• TV Channel: MLB Network
• Live Stream: Watch this game on Fubo

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Matchup Betting Info

• Moneyline Favorite: Guardians -125
• Moneyline Underdog: Astros +105
• Over/Under: 8 runs (Over: -105, Under: -115)

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Astros Probable Starting Pitcher

• Blanco (12-6) will take the mound for the Astros, his 29th start of the season.
• The right-hander’s last appearance was on Saturday, when he threw six innings against the Los Angeles Angels, giving up two earned runs while allowing seven hits.
• He’s looking to extend his two-game quality start streak.
• Blanco will look to pitch five or more innings for the third start in a row.
• He has made 29 appearances and finished eight of them without allowing an earned run.

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Astros Hitting & Pitching Performance

• The Astros have hit 188 homers this season, which ranks 10th in the majors.
• Houston ranks eighth in the majors with a .418 team slugging percentage.
• The Astros have a team batting average of .261 this season, which ranks third among MLB teams.
• Houston ranks 12th in the majors with 731 total runs scored this season.
• The Astros have an on-base percentage of .321 this season, which ranks seventh in the league.
• The Astros are one of the most disciplined teams at the plate this season, ranking third with an average of 7.3 strikeouts per game.
• Houston pitchers have a combined ERA of 3.76 ERA this year, seventh-best in baseball.
• Houston has a 9.3 K/9 rate this season as a pitching staff, third-best in baseball.
• Astros pitchers have a 1.249 WHIP this season, 14th in the majors.

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